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Canada Wide Pharmacy > Drug Category > Women's Health > Vagifem or Equivalent

Vagifem (Estradiol)

TypeDrug NameDosage 
Vagifem10 mcg

Generic Equivalent of Vagifem

No generic equivalents of Vagifem found.



Vagifem (Estradiol) is an Rx medication that is used to treat women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused due to the body making less estrogen and this medication is a female hormone (estrogen). When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as this medication) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.

Vagifem 10 mcg treats menopausal symptoms in and around the vagina. Clinical studies showed that Vagifem 10 mcg reduced a combined score of the most bothersome symptoms, including:
  • Vaginal dryness;
  • Pain and bleeding during intercourse;
  • Irritation;
  • Soreness;
  • Itching in and around the vagina;
  • Painful urination

  • Vagifem 10 mcg treats the underlying cause of menopause-related vaginal changes by helping to replenish the vagina’s lost estrogen. Vagifem (estradiol vaginal inserts) 10 mcg is placed directly into the vagina, right where you’re experiencing changes, to help replenish estrogen lost due to menopause. Vagifem is the same as the body’s estrogen. Not all estrogens are the same; there are several different forms of estrogens and the estrogen used in Vagifem 10 mcg is called “estradiol,” which is the same estrogen that your body makes.

    Even with estradiol, moderation is important. The North American Menopause Society (NAMS) recommends that women take the lowest effective dose of estrogen consistent with the treatment goals their health care provider has established. Vagifem 10 mcg is the lowest dose of vaginal estrogen commercially available which, of course, we are happy to supply.

    Treatment given where it's needed, as we said a little earlier. Vagifem 10 mcg is an insert that you place in your vagina with a convenient, pre-dosed, single-use applicator made of smooth plastic. To help ensure exact dosing, each applicator contains a single insert with 1 dose of Vagifem 10 mcg.

    You can insert the Vagifem 10 mcg insert with the slim applicator while standing up or lying down. You don’t need to wash and reuse the applicator; just dispose of it after use, as you would a tampon applicator.


    Vagifem comes from Canada and is manufactured by Novo Nordisk. This medication is available in doses of 10mcg in the quantities of 18, 36 and 90 estradiol vaginal tablets with applicators. You should always keep Vagifem 10 mcg out of the reach of children. Store at 77 deg F (25 deg C). Do not refrigerate.

    Please note that the manufacturing country and the manufacturer may vary depending on the availability.


    The standard shipping fee is a flat rate of $10.00. Orders are normally dispatched in 2-3 working days after the order is processed. Your package will be delivered by regular mail in 10-14 business days after it is shipped out.

    For more information and further assistance, please feel free to Customer Service at 604-581-4000 or email us at
    • Mailing Address:
    • Canada Wide Pharmacy
    • 102-15129 100 Avenue
    • Surrey, BC, V3R 9P4
    • order by phone 604-581-4000
    • Pharmacist: Yasir Mohamed
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    • Saturday: Closed
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