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Canada Wide Pharmacy > Drug Category > Women's Health > Prometrium or Equivalent

Prometrium (Progesterone)

TypeDrug NameDosage 
Prometrium (Capsule)100 mg

Generic Equivalent of Prometrium

TypeDrug NameDosage 
Progesterone (Capsule)100 mg
Progesterone (Gel Capsule)100 mg

Is A Prescription Required To Purchase Prometrium?

A Prescription is required to acquire Prometrium from licensed online Canadian pharmacies.

What Is The Drug Prometrium Used For?

The drug Prometrium (micronized progesterone) is indicated for use in women with an intact uterus (who have not had surgery for removal of the uterus), who are using estrogen replacement therapy for menopause. The purpose of using Prometrium along with estrogen therapy after menopause is to protect the inner lining of the uterus from overgrowth caused by the estrogen. This medication should be used only under the supervision of a doctor, with regular follow-ups at least once a year to identify the side effects associated with its use. Your doctor may conduct tests in your follow-up visits such as a blood pressure check, a Pap smear, and pelvic exam. You should also undergo a mammogram before starting the treatment and at regular intervals as recommended by your doctor.

How Does Prometrium Work in the Body?

Prometrium contains progesterone, which is a natural female hormone. In healthy women of childbearing age, progesterone is produced by ovaries each month during the second half of the menstrual cycle. Progesterone plays an important role in the monthly shedding of the inner lining of the uterus (known as endometrium) and the menstrual bleeding.

What Is The Generic Form Of Prometrium?

The generic form of Prometrium is progesterone and is manufactured by Teva Pharmaceuticals.

How Is Prometrium Supplied and Stored?

Prometrium comes from Canada and is manufactured by Merck Canada Inc. Prometrium is supplied in the dosage form of 100 mg, and is available in unit dose blister packages, with 30 capsules per package.

The medication should be stored at a temperature between 15 °C and 30 °C, protected from light. It should be kept out of the reach of children and pets.

What Is the Cost of Prometrium?

Our verified online pharmacy is pleased to offer you Prometrium 100 mg at an unbeatable price of $259 for a supply of 90 capsules, which is $2.88 per unit. The generic form of Prometrium is available at a price of $249, for a supply of 100 capsules, which is $2.49 per unit. It is best to compare the prices of drugs online at edrugsearch or Pharmacychecker.Com.

Is Prometrium A Natural Hormone?

Prometrium is a type of micronized progesterone. It is considered as natural progesterone. It is chemically identical to the progesterone hormone that your ovaries produce.

Can Progesterone Help You Lose Weight?

Hormones such as Prometrium can lead to changes in body weight. If you experience any unexpected change in body weight, contact your healthcare professional.

What Is The Best Time Of Day To Take Progesterone?

Progesterone is usually taken once a day in the evening or at bedtime. It should be taken exactly as prescribed by your doctor.

How Should I Take Prometrium?

Prometrium should be used exactly as prescribed by your healthcare professional. The recommended dose of Prometrium for menopause is 2 capsules (200 mg) per day for the last 14 days of estrogen treatment each cycle or 3 capsules per day (300 mg) for the last 12-14 days of estrogen treatment each cycle. If you are being treated with 2 capsules (200 mg) a day you should take them both at bedtime. If you are being treated with 3 capsules (300 mg) a day, you should split the daily dose into two parts by taking one capsule in the morning and two at bedtime.

What Happens If I Overdose Prometrium?

An overdose of Prometrium (progesterone) can nausea, vomiting, sleepiness, dizziness, depressive mood, tiredness, acne, and hairiness. If you accidentally overdose Prometrium or take several capsules at once, consult a doctor.

What Should I Avoid While Taking Prometrium?

Prometrium can lead to dizziness or sleepiness, 1-4 hours after ingestion of the capsules. Hence, before you drive or do anything that requires alertness, make sure you are not experiencing these side effects.

How Safe Is Prometrium?

Prometrium can lead to an increased risk of developing invasive breast cancer, heart attack, stroke and blood clots in both lungs and large veins when used along with estrogen therapy. Estrogens with or without progestins should not be used for prevention of heart disease or stroke or dementia. Estrogens with or without progestins should be used at the lowest effective dose and for the shortest time period possible.

What Are The Possible Side Effects of Prometrium?

Like all other medications, Prometrium can also cause side effects. Most common side effects include genital bleeding or spotting (minor vaginal bleeding), in between the normal periods (mainly during first two months), irregular menstrual periods, dizziness, vertigo, sleepiness, abdominal discomfort (cramps, pain and pressure in the abdomen), nausea, fatigue, , aggravation of migraine headaches, headaches, fainting, light-headedness, depressed mood, breast tenderness or swelling, liver disease. Side effects observed in women taking progestins, in general, include allergic reaction including hives, skin redness, swelling, wheezing, increased heart rate, difficulty breathing, rash with or without itching, rare cases of loss of consciousness, hot flashes, impaired concentration, confusion, swelling and difficulty with speech. Other side effects that have been observed with estrogen and progestin combinations in general, but not necessarily with Prometrium are mentioned below:
  • Water retention (bloating and swelling)
  • Overgrowth of the lining of the uterus
  • Gallbladder disorder, impaired liver function, jaundice (yellowing of the eyes or skin);
  • Menstrual cramps, vaginal itching/discharge
  • Pain during sexual intercourse
  • Pain on urination or difficulty urinating
  • Premenstrual syndrome (PMS)
  • Breast tenderness
  • Inflammation of the bladder
  • Brown, blotchy spots on the exposed skin (pregnancy mask)
  • Skin rash, tender red lumps or nodules or other skin reactions
  • Loss of hair, hairiness, acne
  • Palpitations (an unpleasant sensation of irregular and/or forceful beating of the heart)
  • Pain, swelling or redness of the calf or leg which may indicate a blood clot
  • Chest pain or shortness of breath which may indicate a blood clot
  • Increase in blood pressure
  • Depression, nervousness, irritability
  • Visual disturbances, intolerance to contact lenses
  • Changes in appetite and body weight
  • Change in sexual drive
  • Pain in the joints and muscles, usually lasting only 3-6 weeks
  • A headache
During the first 2-4 months of your hormone replacement therapy (HRT), you might experience unscheduled vaginal bleeding (at times other than when you would expect a normal period). This is a normal response of your body as it is adjusting to the return of estrogen and progesterone levels that were seen before menopause. If this unscheduled or abnormal vaginal bleeding persists, contact your doctor.

When Should You Not Use Prometrium?

Do not use Prometrium if you:
  • Have had an allergic or unusual reaction to progesterone, soya, peanut or any other component of Prometrium
  • Have liver disease
  • Have or have had cancer or abnormalities of the breast or uterus
  • Have overgrowth of the lining of the uterus
  • Have undiagnosed or unexpected vaginal bleeding
  • Have a history of heart diseases such as heart attack or stroke
  • Have migraine headaches
  • Have or have had an abnormal increase in blood clotting
  • Have partial or complete loss of vision due to blood vessel disease of the eye
  • Are pregnant or might become pregnant

What Should You Tell Your Doctor Before Using Prometrium?

Before you start using Prometrium, be sure to tell your doctor if you:
  • Have a history of allergy or intolerance to Prometrium or any of its ingredients
  • Are allergic to soy or peanut or other substances or medications
  • Have a history of liver disease or jaundice (yellowing of the eyes and/or skin) or itching related to estrogen use or during pregnancy
  • Have a personal history of breast diseases such as breast lumps, breast biopsies or family history of breast cancer
  • Have had unexpected or undiagnosed vaginal bleeding
  • Have a history of uterine fibroids or endometriosis (overgrowth of the lining of the uterus)
  • Have been diagnosed with lupus
  • Have a history of heart disease, heart attack or stroke
  • Have a history of migraine headaches
  • Have a personal or family history of blood clots or a personal history of active thrombophlebitis (inflammation of the veins)
  • Have partial or complete loss of vision due to blood vessel disease of the eye
  • Are pregnant or might become pregnant
  • Have a history of high blood pressure
  • Have a history of kidney disease
  • Have a history of epilepsy (Seizures)
  • have a history of bone disease (including certain metabolic conditions or cancers that can affect blood levels of calcium and phosphorus)
  • Have a history of asthma
  • Have been diagnosed with diabetes
  • Have been diagnosed with porphyria (a disease of blood pigment)
  • Have a history of high cholesterol or triglyceride levels
  • Have a history of depression
  • Have had surgical removal of the uterus
  • Smoke

What Medicines Can Interact With Prometrium?

It is important to tell your healthcare professional about all other medicines that you have taken recently including any kind of supplements and non-prescription drugs.

Medicines which interact with Prometrium include:
  • Anti-seizure medications like carbamazepine, phenytoin
  • Antibiotics such as erythromycin, clarithromycin, penicillin, tetracycline
  • Antifungal medications such as ketoconazole, rifampin
  • St. John's Wort

Where Can I Buy Prometrium Online?

If prescribed by your healthcare professional, Prometrium can be bought directly from Canadian Online Pharmacy. You will not have to wait to start your therapy due to the swift shipping service provided by us.

How Is Prometrium Delivered?

The standard delivery fee is $10.00. The orders are usually shipped in 2-3 working days after the processing of the order. The medication package is delivered by regular mail within 10-14 business days after it has been shipped.

For further information and aid, you can contact our Customer Service at 1877-240-4438 or email us at


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