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Pristiq (Desvenlafaxine Extended Release)

TypeDrug NameDosage 
Pristiq50 mg
Pristiq100 mg

Generic Equivalent of Pristiq

TypeDrug NameDosage 
Desvenlafaxine Extended Release50 mg
Desvenlafaxine Extended Release100 mg

Is A Prescription Required To Acquire Pristiq?

A Prescription is required to purchase Pristiq at

What Is the Drug Pristiq Used for?

Pristiq is a medication prescribed by doctors for the treatment of depression, defined as a serious medical illness that negatively impacts the feelings and actions of a person (Major depressive disorder).

Desvenlafaxine) is a serotonin and norepinephrine reuptake inhibitor (SNRI) and acts by affecting the actions of two chemicals in brain: serotonin and norepinephrine. Pristiq is an extended release desvenlafaxine succinate tablet. The inactive ingredients of this tablet include hypromellose, microcrystalline cellulose, talc, magnesium stearate and film coating, which, consists of polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, iron oxide and FD&C yellow #6.

How Is Pristiq Supplied and Stored?

Desvenlafaxine succinate, under the brand name of Pristq is a product of Pfizer Inc. It will be our privilege to offer you the branded Pristiq medication from Canada.

Pristiq is available in following doses and quantities: 50 mg tablets available in 90 tablets and 100 mg tablets available in 90 tablets. This medication should be stored at a temperature of 15°C to 30°C and should be kept out of the reach and sight of children. Pristiq should not be used beyond the expiration date mentioned on the package.

What Is the Cost of Pristiq?

The lowest CanadaWidePharmacy price for the most popular branded Pristiq from Pfizer is approximately $5 per tablet, 87% off the average retail price of $9 per tablet. It is good to compare the best prices of Pristiq from licensed online pharmacies in Canada.

Are Pristiq and Effexor Are the Same?

Both Pristiq and Effexor are both SNRI and used for the treatment of depression. Effexor is generic form of venlafaxine and Pristiq (desvenlafaxine) is a major metabolite of Effexor (Venlafaxine).

Can Pristiq Make You Gain Weight?

Pristiq has not been associated with significant changes in weight during treatment. If you notice any changes in your weight, it is best to consult your health care provider.

How Is Pristiq Taken?

Pristiq is intended for oral use. The drug can be taken with or without food. The tablets are intended to be swollen whole with fluid. Do not chew, crush, cut or dissolve the tablet. Remember to follow the instructions of your health care professional while taking Pristiq.

How Fast Does Pristiq Act?

Pristiq should be given some time to act completely and show full efficacy. It can take several weeks for an antidepressant to show its complete action, however it may be sooner for some people. It is important to stick to the prescribed routine of the medication to get complete benefit.

How Is Pristiq Metabolized?

Desvenlafaxine is metabolized in liver and has a half-life of 11 hours.

What Are The Possible Side Effects of Pristiq?

The most common side effects that can be experienced while using Pristiq are: nausea, dry mouth, constipation, fatigue, decreased appetite, sweating, dizziness and trouble in sleeping. For most of the patients, these side effects are minor and temporary. Some common side effects include increase in heart rate, ringing in ears, vertigo, dilation of pupils, blurring of vision, vomiting, diarrhea, anxiety, nervousness, chills, irritability, urinary hesitation, delayed ejaculation in men, rashes, hot flushes, drowsiness and stiffness of muscles. However, these are not all the side effects of Pristiq. Call your health care professional right away if the side effects become serious, or if you notice any side effect not mentioned here, or if there is any side effect that worries you.

How Safe Is Pristiq?

Pristiq can be taken by both men and women; however its safety has not been established for use in pregnancy. Pristiq is also excreted in human milk. Hence, you should inform your doctor if you become pregnant or are planning a pregnancy or are breastfeeding. It is also important not to operate any machines or tools until you know how the drug affects you. Avoid drinking alcohol while you are on Pristiq. In case of any further questions about Pristiq, consult your health care professional.

When Should You Not Take Pristiq?

Do not take Pristiq if you:
  • Are taking or have recently taken Monoamine Oxidase Inhibitors (MAOIs).
  • Have abnormal lab reports
  • Are taking any anti-coagulant medications such as aspirin and warfarin.
  • Are allergic to desvenlafaxine, or any other ingredients of Pristiq
  • Are taking or have recently taken other medications containing desvenlafaxine
  • Are taking any prescription or non-prescription medications including supplements.
It is important to note that everyone might not be able to use Pristiq. It is only your health care professional who can decide whether Pristiq is right medication for you or not. Before taking Pristiq always tell your doctor about all your medical issues including if,
  • You are taking other medications or other nutritional and herbal supplements
  • You have a history of heart diseases, high blood pressure
  • You have blockage in gastrointestinal tract (oesophagus, stomach or intestine)
  • You have glaucoma
  • You have low blood sodium levels
  • You have history of seizures or fits
  • You have a bleeding disorder or low platelet count
  • You had a recent bone fracture or are at the risk of osteoporosis
  • You have history of high cholesterol
  • You have family history of bipolar disorder or mania
  • You have any kidney disease
  • You are pregnant or planning a pregnancy
  • You are breast-feeding
Pristiq should not be given to children or adolescents under 18 years of age.

What Other Medicines Can Affect Pristiq?

It is important that you tell your health care professional about all the prescription and non-prescription medications, vitamins and supplements you have been taking. Pristiq and other medications can affect each other’s actions. Always confirm with your doctor before starting or stopping any medicines. Especially tell your doctor if you are taking any of the following:
  • Monoamine Oxidase inhibitors
  • Anticoagulants such as aspirin or warfarin
  • Medicines containing venlafaxine or desvenlafaxine
Serotonin syndrome or neuroleptic malignant syndrome (NMS)-like reactions is a rare, but life-threatening condition that can lead to serious changes in brain, muscles and digestive system functioning. It can occur when Pristiq is taken along with medications such as:
  • Medicines to treat migraine like triptans
  • Medicines to treat mood disorders such as tricyclic antidepressants, lithium, selective serotonin reuptake inhibitors (SSRIs), SNRIs and anti-psychotics
  • Medications used to treat pain like fentanyl, tramadol, methadone, meperidine, pentazocine
  • Medications for treating cough like dextromethorphan
  • St. John’s Wart
  • MAOIs
  • Linezolid, an antibiotic
  • Tryptophan supplements
Before taking any of the above medications and Pristiq together, remember to consult your health care professional. Signs and symptoms of serotonin Syndrome include: Agitation, restlessness, confusion, hallucinations, muscle stiffness and twitching, loss of coordination, increased heartbeat and body temperature, diarrhea, nausea, vomiting, overactive reflexes and coma.

Where Can I Buy Pristiq Online?

If you have been prescribed Pristiq by your health care professional, you can buy it directly from Canadian Online Pharmacy. The quick shipping service will not make you wait for the start of your therapy.

How Is Pristiq Delivered?

The standard delivery fee is $10.00. The orders are usually shipped in 2-3 working days after the processing of the order. The medication package is delivered by regular mail within 10-14 business days after it has been shipped. For further information and aid, you can contact our Customer Service at 604-581-4000 or email us at



  • Mailing Address:
  • Canada Wide Pharmacy
  • 102-15129 100 Avenue
  • Surrey, BC, V3R 9P4
  • order by phone 604-581-4000
  • Pharmacist: Yasir Mohamed
  • Pharmacy Hours:
  • Weekdays: 9:00AM - 5:00PM
  • Weekends: Closed