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Evista (Raloxifene)

TypeDrug NameDosage 
Evista60 mg

Generic Equivalent of Evista

TypeDrug NameDosage 
Raloxifene60 mg
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Is A Prescription Required To Purchase Evista?

A Prescription is required to have Evista from our Canadawide drug pharmacy.

What Is the Drug Evista Used for?

Evista is indicated for the treatment or prevention of osteoporosis in postmenopausal women. It is also prescribed for reduction in risk of breast cancer in postmenopausal women with osteoporosis.

How Does Evista Work?

Evista (raloxifene) is an estrogen agonist/antagonist most commonly known as selective estrogen receptor modulator (SERM). It acts by binding to estrogen receptors, thus activating the estrogenic pathways is some tissues (agonism) and blockade of estrogenic pathways in others (antagonism). It acts as an agonist in bone thus increasing bone mineral density (BMD) and decreasing fracture incidence.

Is Evista a Hormone?

Evista is a hormone therapy, and belongs to the class of benzothiophene compounds. It is classified as Selective Estrogen Receptor Modulator (SERM).

Is Raloxifene a Bisphosphonate?

Both biophosphonates and raloxifene are indicated for prevention and treatment of postmenopausal osteoporosis; however these medications have different safety as well as efficacy profiles and different mechanism of action.

Is Evista a Cancer Medication?

Evista will not treat breast cancer and is not a cancer medication. It is only used for reducing the risk of invasive breast cancer in postmenopausal women.

Is Evista A Hormone Replacement Therapy?

Estrogen replacement therapy after menopause increases the risk of breast or ovarian cancer. That is why Evista is used, as an estrogen knock off drug for prevention of osteoporosis and reducing the risk of breast cancer. It is not recommended to combine Evista with hormone replacement therapy (ERT or HRT) since there is limited safety information and no studies have been conducted to study the effectiveness of this combination.

Is There a Generic Equivalent of Evista?

The generic equivalent of Evista is raloxifene that belongs to benzothiophene class of compounds. It is manufactured by Teva Pharmaceuticals.

How Is Evista Supplied and Stored?

Raloxifene (generic equivalent of Evista) is supplied as 60 mg dosage in bottles of 90 tablets.

The medication should be kept at a room temperature of 15°C to 30°C in its original packing in a dry place. It should be stored out of reach and sight of children.

What Is the Cost of Generic Evista?

Canada Wide pharmacy is pleased to offer you the generic Evista (raloxifene) 60 mg at an unbeatable price of $88 for a supply of 90 tablets, which is $0.88 per tablet. The average retail price for brand Evista price around $6.45, and the version of Raloxifene costs $1.06 per tablet. Compare and save more on Canadian prescription drugs!

How Is Evista Taken?

The usual dose of Evista is 60 mg once a day, any time of the day with or without food. The medication should be taken exactly as prescribed by your doctor or pharmacist. Follow the directions on the prescription label of Evista (raloxifene).

How is Evista Metabolized in Body?

Evista (raloxifene) is metabolized extensively in liver and has a half-life of approximately 27.7 hours.

How Long Take Evista for Osteoporosis?

It is best to dscuss your concerns with your health care professional, to see what he/she have to say about its long-term use. He will weigh the risks against the benefits for each individual patient to decide the treatment period with Evista.

What Are The Possible Side Effects of Evista?

Like all other medications, Evista can also cause side effects. The most common side effects leg cramps, hot flashes, arthralgia, sweating and flu-like symptoms. Evista can lead to increased risk of blood clots in lungs and veins. You should immediately consult your health care professional if you experience
  • Redness, swelling, pain and heat in your calves or legs
  • Sudden change in vision
  • Sudden chest pain or shortness of breath
Evista does not have any adverse effects on uterus, breast or mental function. Hence, any unexplained pain in breasts, breast enlargement, uterine bleeding, change in mood should be reported to the doctor or pharmacist.

When Should You Not Take Evista?

Do not take Evista if you:
  • Are allergic to raloxifene or any other ingredients of Evista
  • Have not passed menopause. Evista is indicated for use only in postmenopausal women
  • Are pregnant or could become pregnant as Evista can cause harm to your unborn child
  • Are breast-feeding as it is unknown if Evista passes into breast milk and what effects it might have on the baby
  • Have or had blood clots in veins that required treatment, such as clots in legs, lungs or eyes, since Evista can increase the risk of developing these blood clots

What Should You Tell Your Doctor Before taking Evista?

Before you start taking Evista, be sure to tell your doctor if you:
  • Are pregnant, breast feeding or still get menstrual bleeds or had menstrual bleeds in the past year
  • Have or had an allergic reaction to any medicine you had taken
  • Are intolerant to lactose as Evista contains lactose
  • Have or had liver problems
  • Have or had blood clots in veins
  • Take blood thinners such as warfarin or coumarin derivatives
  • Are taking any other medications including prescription, non-prescription drugs, vitamins and other herbal supplements
  • Had high levels of triglycerides in past due to estrogen treatment
  • Had a stroke or are at the risk of stroke (have irregular heartbeats)
  • Have been immobile for a long time as this can increase the risk of blood clots in veins that can be further increased by Evista. If you plan to be immobile, such as staying in bed after surgery or plan a long trip, you should stop taking Evista at least before 3 days to reduce the risk of blood clotting in veins.

What Medicines Can Interact With Evista?

It is important to tell your health care professional about all other medicines that you have taken recently including any kind of supplements and non-prescription drugs.

Following medicines can interact with Evista:
  • Questran, Questran Light, Alti-Cholestyramine Light, Novo-Cholamine, Novo-Cholamine Light, PMS-Cholestryramine (products containing cholestyramine) reduce the effectiveness of Evista. Therefore, you should not take cholestyramine while taking Evista.
  • Hormone replacement therapy (ERT or HRT) since there is limited safety information and no studies have been conducted to find the effectiveness of this combination.
  • Warfarin (prothrombin time should be monitored when starting or stopping Evista).
  • Diazepam, diazoxide and lidocaine. These drugs are highly protein bound and should be used in caution in patients taking Evista.
Clinical trials included giving Evista with commonly prescribed medicines such as acetaminophen, digoxin, non-steroidal anti-inflammatory drugs (NSAIDS) and oral antibiotics. No problems or interactions were observed. However, each patient is different and so you should always consult with your health care professional before taking any medication.

Where Can I Buy Evista Online?

If prescribed by your health care professional, Evista can be bought directly from Canadian Online Pharmacy. You will not have to wait to start your therapy due to the swift shipping service provided by us.

How Is Evista Delivered?

The standard delivery fee is $10.00. The orders are usually shipped in 2-3 working days after the processing of the order. The medication package is delivered by regular mail within 10-14 business days after it has been shipped.

For further information and aid, you can contact our Customer Service at 604-581-4000 or email us at customerservice@canadawidepharmacy.com.

References:

1. https://www.webmd.com/osteoporosis/news/20010321/evista-estrogen-drug-many-benefits-few-drawbacks#1
2. https://www.lilly.ca/en/pdf/product-monograph/evista-pm_pristine_oct-10-2008_mkg.pdf
3. http://pi.lilly.com/us/evista-pi.pdf
4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/022042lbl.pdf 5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642779/
RETAIL PHARMACY
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  • 102-15129 100 Avenue
  • Surrey, BC, V3R 9P4
  • order by phone 604-581-4000
  • Pharmacist: Yasir Mohamed
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