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Efudex Cream (Fluorouracil)

TypeDrug NameDosage 
Efudex Cream5 %/40 gm

Generic Equivalent of Efudex Cream

No generic equivalents of Efudex Cream found.


Is A Prescription Required To have Efudex?

A Prescription is required to purchase Efudex from licensed online Canadian pharmacies.

What Is Efudex Cream Used For?

Efudex cream is used to treat skin problems including cancer or conditions that could become cancerous if not treated such as multiple actinic or solar keratosis, superficial basal cell carcinoma.

How Does Efudex Cream Work?

The cream Efudex contains fluorouracil, which belongs to a class of drugs known as antimetabolites. It interferes with the growth of the abnormal cells and destroys them eventually.

How Is Efudex Supplied and Stored?

Efudex is manufactured by Valeant Pharmaceuticals, Inc and is available as 5% cream in quantity of 40 g.

The medication should be stored at room temperature, protected from heat, moisture and direct light. It should be kept out of sight and reach of children.

What Is the Cost of Efudex Cream?

Our verified online pharmacy is pleased to offer you the generic Efudex 5%, 40 g at an unbeatable price of $150 for a quantity of 2, which is $75 per unit. It is best to compare the prices of drugs online at edrugsearch or Pharmacychecker.Com.

Is Efudex A Form Of Chemotherapy?

Efudex (Fluorouracil) is a type of chemotherapy and exerts its cancer effect by preventing the production of DNA in abnormal cells.

Can I Use Efudex For Warts?

Efudex cream is approved by FDA for treatment of actinic keratoses and basal cell carcinomas. It has not been approved for treatment of warts but is being considered as an off label medicine for treatment of planatar warts with tape.

How Long Do You Use Efudex For?

Continue to use Efudex for as long as your doctor tells you. The treatment of keratosis is usually for 2 to 4 weeks and for basal cell carcinoma is 3 to 6 weeks. Destruction of cells may take 10 to 12 weeks.

How Should I Use Efudex Cream?

Use Efudex cream exactly as prescribed by your health care professional. Follow your doctor’s instructions on dosage and length of treatment. Apply enough medication each time to cover the entire affected area with a thin layer. Apply Efudex after washing the area with soap and water and drying carefully. Efudex should be applied carefully near the eyes, nostrils and mouth. Efudex may result in redness, soreness, scaling and peeling of the affected skin after 1 to 2 weeks of its use. This effect may last for several weeks after you stop applying Efudex and is usually expected. Do not stop applying the medication without consulting your doctor first. If the reaction is very uncomfortable, consult your doctor.

What Should I Avoid While Using Efudex?

When using Efudex, and after 1 or 2 months of stopping its use, your skin may become more sensitive to sunlight than usual and excess sunlight may increase the effect of Efudex. During treatment with Efudex, stay out of direct sunlight, especially between 10 am and 3 pm if possible. Try to wear protective clothing, along with hat and sunglasses. Apply sunscreen that has a skin protection factor of at least 15. Patients with a fair complexion may require a higher SPF number. Do not use sunlamp or tanning bed or booth. If you have any severe reactions from sun, consult your doctor.

What Are The Possible Side Effects of Efudex?

Like all other medications, Efudex can also cause side effects. Most common side effects include burning sensation where the medication is applied, increased sensitivity of skin to sunlight, oozing, skin rash, soreness or tenderness of skin. Other less common side effects include darkening of skin, scaling, watery eyes. Consult your doctor if redness and swelling of normal skin occurs. These are not all the side effects of Efudex. Consult your doctor if you experience any unexpected effects.

When Should You Not Take Efudex?

Do not take Efudex if you:
  • Are allergic to fluorouracil or any other ingredients in Efudex
  • Have Dihydropyrimidine dehydrogenase (DPD) deficiency
  • Are pregnant or planning to become pregnant. Efudex can be absorbed through skin and cause birth defects in unborn baby
  • Are breast-feeding or planning to do so

What Should You Tell Your Doctor Before taking Efudex?

Before you start taking Efudex, be sure to tell your doctor if you:
  • Have any medical problems. Presence of other medical problems may affect the use of Efudex on skin. Other skin problems can get aggravated with use of Efudex
  • Are pregnant or plan to become pregnant or are breast-feeding
  • If you are an elderly. Many medicines have not been studied in older people.
Therefore, it may not be known whether they work exactly the same way they do in youger patients. Although there is no specific information comparing the use of this medication in other age groups, it is not expected to cause different side effects or problems in older people than in younger adults.

What Medicines Can Interact With Efudex?

Although, no specific interactions with other medications have been reported on use of Efudex, it is important to tell your health care professional about all other medicines that you have taken recently including any kind of supplements and non-prescription drugs.

Where Can I Buy Efudex Online?

If prescribed by your health care professional, Efudex can be bought directly from Canadian Online Pharmacy. You will not have to wait to start your therapy due to the swift shipping service provided by us.

How Is Efudex Delivered?

The standard delivery fee is $10.00. The orders are usually shipped in 2-3 working days after the processing of the order. The medication package is delivered by regular mail within 10-14 business days after it has been shipped.

For further information and aid, you can contact our Customer Service at 1877-240-4438 or email us at


  • Mailing Address:
  • Canada Wide Pharmacy
  • 102-15129 100 Avenue
  • Surrey, BC, V3R 9P4
  • order by phone 604-581-4000
  • Pharmacist: Yasir Mohamed
  • Pharmacy Hours:
  • Weekdays: 9:00AM - 5:00PM
  • Saturday: Closed
  • Sunday: 9:00AM - 2:00PM