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Depakene (Valproic Acid)

TypeDrug NameDosage 
Depakene (Oral Syrup)50 mg/ml/240 ml

Generic Equivalent of Depakene

TypeDrug NameDosage 
Valproic Acid (Oral Syrup)50 mg/ml/480 ml
Valproic Acid250 mg
Valproic Acid (ON BACKORDER)500 mg
  • DETAILS
  • SAFETY
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Is A Prescription Required To Purchase Depakene?

A Prescription is required to acquire Depakene from our online pharmacy Canada wide.

What Is Depakene Used for?

Depakene is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Depakene is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches. Safety and efficacy have not been established in children with epilepsy younger than 10 years of age, and in children with migraine younger than 12 years of age. Because of valproic acid's toxicity, use in children younger than 2 years of age requires extreme caution.

What Does Depakene Do To The Body?

Depakene (Valproic acid) has anticonvulsant properties. The mechanism of action has not yet been established. It has been suggested that its activity in epilepsy is related to increased brain concentrations of gamma-aminobutyric acid (GABA). It may work by restoring the balance of certain natural substances (neurotransmitters) in the brain.

What Is the Generic Form of Depakene?

The generic form of Depakene is Valproic Acid..

How Is Depakene Supplied and Stored?

The brand Depakene is manufactured by BGP Pharma and is available in dosage forms of 50 mg/ml/240 ml oral syrup. The generic version of Depakene (Valproic Acid) is available as 50 mg/ml/480 ml oral syrup and 250 mg and 500 mg capsules and comes from a different manufacturer.
The medication should be stored at a temperature between 15°C and 30°C, away from warm and damp places. It should be kept out of sight and reach of children.

What Is the Cost of Depakene?

Our Canadawide online pharmacy is pleased to offer you the generic Depakene 250 mg capsules at an unbeatable price of $36 for a supply of 100 capsules, which is $0.36 per unit. The generic form of Depakene (Valproic Acid) 500 mg is available at a price of $66 for a supply of 100 capsules which is $0.66 per unit. The average cost for Depakene 50 mg/ml/240 ml oral syrup is around $51 per unit. It is always best to compare the prices of this medication online at edrugsearch or Pharmacychecker.Com.

Is There A Difference Between Depakene And Valproic Acid?

Depakene contains Valproic Acid as its active ingredient. The generic form of Depakene is known as Valproic Acid.

How Should I Take Depakene?

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Swallow the delayed-release capsules or oral capsules whole with a full glass of water. Do not split, crush, or chew it. You may take this medicine with food to decrease stomach upset. If you cannot swallow the capsule whole, you may open it and sprinkle the contents onto a small amount of soft food (including applesauce or pudding). Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

Is Depakene safe for women of child bearing age?

All women of childbearing age who are being treated with Depakene should talk to their healthcare providers about using other possible treatments instead of Depakene. If the decision is made to use Depakene, you must use an effective method of birth control (contraception).

What does Depakene do to the brain?

Brain cells need to work (fire) at a certain rate to function normally. During a seizure, brain cells are forced to work much more rapidly than normal. Valproic acid helps prevent brain cells from working as fast as a seizure requires them to.

Does Depakene make you sleepy?

You may feel sleepy, tired or dizzy when you first start taking valproic acid. This may also happen if your dose has increased.

What Are The Possible Side Effects of Depakene?

Like all other medications, Depakene can also cause side effects. The most commonly reported adverse reactions include nausea; vomiting; indigestion; sleepiness; headache; diarrhea; weakness; tremor and dizziness. Changes in hair are also reported, such as hair loss or in increase in hair on face, chest and back. Some of the serious side effects include hallucinations. Uncommon side effects include brain dysfunction from high ammonia levels in the blood (tiredness, vomiting, abnormal walking, extreme irritability, combative/bizarre behaviour, refusal to eat meat or high protein products); decreased number of platelets in the blood; liver disorder (weakness, tiredness, abdominal pain, diarrhea, facial swelling, loss of appetite, yellowing of the skin or eyes, dark urine, nausea, and vomiting); pancreas disorder (abdominal pain, nausea, vomiting, and/or loss of appetite); thoughts of suicide or hurting yourself. This is not a complete list of side effects. For any unexpected effects while taking Depakene, contact your doctor or pharmacist.

When Should You Not Take Depakene?

Do not take Depakene if you:

  • Are allergic to the drug;
  • Are pregnant or breast feeding;
  • Have liver disease or significant liver dysfunction;
  • Have mitochondrial diseases (e.g., Alpers or AlpersHuttenlocher disease);
  • Have known urea cycle disorders (a genetic disorder);
  • Have porphyria (a genetic disorder).
  • What Should You Tell Your Doctor before taking Depakene?

    Before you start taking Depakene, be sure to tell your doctor if you:

  • Are allergic to any component of Depakene capsules or oral solution;
  • Are pregnant or are planning to become pregnant;
  • Are breast-feeding (nursing); Depakene passes into breast milk;
  • Are taking any other prescription or over the counter medicine;
  • Consume alcohol on a regular basis;
  • Have a history of, or suffer from a liver disease, such as jaundice (yellowing of the skin and eyes);
  • Have ever had an unusual or allergic reaction to Depakene (including fever or rash);
  • Have kidney disease;
  • Have other medical conditions including a history of unexplained coma, intellectual disability or any type of brain dysfunction;
  • Have a psychiatric disorder or have thoughts of suicide.

  • Depakene can lead to a slight increase in blood sugar. You are likely at the risk of developing diabetes if you have high fat or sugar levels in your blood or are overweight. Discuss the risks of developing diabetes with your doctor. If you take Depakene during pregnancy, your child has a higher risk for birth defects and adverse effects on IQ and brain development, which can begin early in the pregnancy, even before you know that you are pregnant. There may be other medications to treat your condition that have a lower chance of birth defects.

    What Medicines Can Interact With Depakene?

    It is important to tell your health care professional about all other medicines that you have taken recently including any kind of supplements and non-prescription drugs. Medicines which interact with Depakene include:

  • Anticonvulsants such as carbamazepine, lamotrigine, felbamate, phenytoin, ethosuximide, phenobarbital;
  • Anticoagulants such as acetylsalicylic acid, warfarin, dicumarol;
  • Antipsychotics;
  • Any of the group of antibiotics in the carbapenem class such as doripenem, ertapenem, imipenem, meropenem;
  • Benzodiazepines such as diazepam, lorazepam, clonazepam;
  • Medicines used to treat depression such as selective serotonin re-uptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants such as amitriptyline, nortriptyline;
  • Some medicines used to treat infections such as rifampin;
  • Some medicines used to treat diabetes such as tolbutamide;
  • Some HIV-antiviral medication such as zidovudine;
  • Some medicines used to treat heartburn and peptic ulcers such as cimetidine.
  • Where Can I Buy Depakene Online?

    If prescribed by your health care professional, Depakene can be bought directly from Canadian Online Pharmacy. You will not have to wait to start your therapy due to the swift shipping service provided by us.

    How Is Depakene Delivered?

    The standard delivery fee is $10.00. The orders are usually shipped in 2-3 working days after the processing of the order. The medication package is delivered by regular mail within 10-14 business days after it has been shipped. For further information and aid, you can contact our Customer Service at 604-581-4000 or email us at customerservice@canadawidepharmacy.com.

    References:

    https://www.mylan.ca/-/media/mylanca/documents/english/product%20pdf/pdfs%20dec%202015/depakene-pm-2016.01.08.pdf
    https://www.webmd.com/drugs/2/drug-9702-19/depakene-oral/valproic-acid-oral/details
    https://www.drugs.com/cons/depakene.html#uses
    https://www.rxlist.com/depakene-drug.htm
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