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Canada Wide Pharmacy > Drug Category > Women's Health > Climara Patch or Equivalent

Climara Patch (Estradiol Hemihydrate)

TypeDrug NameDosage 
Climara Patch25 mcg
Climara Patch50 mcg
Climara Patch75 mcg
Climara Patch (Discontinued)100 mcg

Generic Equivalent of Climara Patch

No generic equivalents of Climara Patch found.


Is A Prescription Required To Purchase Climara Patch?

A Prescription is required to acquire Climara Patch from licensed online Canadawide pharmacies.

What Is The Drug Climara Patch Used For?

Climara is indicated and used for the following conditions:
  • Treatment of menopause symptoms (moderate to severe hot flashes). Estrogens are hormones produced by a woman's ovaries. When her menstrual periods stop (menopause), around the age of 45-50, the ovaries stop producing estrogens. Sometimes ovaries are removed by an operation and it is known as surgical menopause. The drop in estrogen levels causes uncomfortable symptoms in women such as the feeling of warmth in face, neck, and chest or a sudden intense episode of heat and sweating (known as hot flashes). These hot flashes can further lead to frequent awakening at night, irritability, sleep disturbance and depression.
  • Treatment of moderate to severe dryness, itching, burning and itching around the vagina, which occurs due to estrogen deficiency.
  • Prevention of the development of osteoporosis. After menopause, all women start to lose calcium in their bones due to a decrease in the amount of estrogen in their body. With time, it may lead to thinning of bones called as osteoporosis which makes them weak and increases the chances of fractures.
  • Treatment of conditions in which a young woman’s ovaries do not produce enough estrogen naturally.
Women with an intact uterus should use always Climara Patch along with a progestin.

How Does Climara Patch Work in the Body?

Climara is a medicated transdermal patch that contains a hormone called estrogen (estradiol), the same as the hormone produced naturally in the body. When you place this patch on your skin, the hormone is transferred to your body through your skin.

How Is Climara Patch Supplied and Stored?

Climara Patch comes from Canada and is manufactured by Bayer. The Climara Patch is available in four sizes: Climara 25 (containing 2.0 mg of estradiol), Climara 50 (containing 3.8 mg of estradiol), Climara 75 (containing 5.7 mg of estradiol) and Climara 100 containing 7.6 mg of estradiol). Each box of Climara contains 4 patches.

Climara Patch should be kept in its sealed pouch until it's ready for use. Store the patch at room temperature between 15°C and 30°C. Do not freeze. Apply Climara Patch immediately upon removal from its pouch. It should be kept out of sight and reach of children.

What Is the Cost of Climara Patch?

Our verified online pharmacy is pleased to offer you the Climara 50 at an unbeatable price of $259 for a supply of 24 patches, which is $10.79 per unit. It is best to compare the prices of drugs online at edrugsearch or Pharmacychecker.Com.

Is Climara A Bioidentical Hormone?

Bioidentical hormones are the manufactured copies of the same hormone that your body uses. Some of the FDA approved therapies for menopause such as Climara Patch contain the same bioidentical form of estrogen as the hormone formulations compounded in a pharmacy.

Do HRT Patches Make You Gain Weight?

HRT (hormone replacement therapy) patches such as Climara Patch can lead to changes in body weight such as weight gain. How Long Does It Take To Feel The Effects Of Hormone Replacement Therapy? It might take a few weeks before you feel the benefits of hormone replacement therapy (HRT) such as Climara Patch. It can take up to three months to feel the complete effects of the therapy.

Can You Cut A Climara Patch?

Studies have not yet proved whether matrix based patches such as Climara should be cut or not. However, some clinicians believe it is probably okay to cut the patches to deliver lower dose to the body. However, most manufacturers do not recommend cutting or altering patches in any way, regardless of the patch type.

Where Do You Put The Climara Patch?

Apply the adhesive side of the patch to a clean dry area of the skin on the trunk of your body or buttocks. Do not apply Climara Patch to breasts due to potentially harmful effects of the medication on breast tissue. Avoid applying the patch on the waistline as tight clothing may rub and remove the patch. The sites where you apply the patch must be rotated with an interval of at least 1 week. The area where you want to apply the patch must not be oily, damaged or irritated. Apply the patch immediately after opening the pouch and remove the protective liner. Then, press the patch firmly in its place for 10 seconds making sure there is good contact especially around the edges. The Climara Patch should be worn continuously for 1 week.

When Should I Apply A Climara Patch?

Climara Patch should be changed once a week. When you change the patch, remove the used Climara Patch and discard it. Throw it away safely out of the reach of children or pets. Rub off any adhesive that might remain on your skin. Then place the new patch on a different site (same sin should not be used again for at least 1 week after removal of the patch). Contact with water, while swimming, bathing or showering will not affect the patch. In case the patch falls off, a new patch should be applied for the remaining of a 7-day dosing interval.

What To Do If Your Skin Becomes Red Or Irritated Under Or Around The Patch?

As is the case with any product that covers the skin for a period of time (such as bandages), Climara Patch can also cause some skin irritation in certain women. This varies according to the sensitivity of each woman. Usually, the redness does not pose any health risks to you, but to reduce this problem you can choose buttocks as the site of application, change the site of application of Climara Patch every time a new patch is applied. If redness continues, consult your healthcare professional.

What Happens If I Overdose A Climara Patch?

An overdose of Climara Patch (estrogen) can lead to nausea, breast discomfort, bloating and vaginal bleeding. If you think you have overdosed a Climara Patch, remove the patch and consult your doctor.

Can I Drink Alcohol While Using A Climara Patch?

It is good to avoid alcohol while using a Climara Patch as acute alcohol intake while using Climara Patch can lead to increased levels of circulating estradiol. Can I Drink Grapefruit Juice While Using A Climara Patch? Grapefruit Juice can increase the concentrations of estrogen in the body, resulting in side effects. Hence, drinking grapefruit juiced should be avoided while using the Climara Patch.

How Safe Is A Climara Patch?

Use of estrogens with progestins can lead to increased risk of developing breast cancer, heart attack, stroke and blood clots in both lungs and large veins. Use of estrogen alone therapy increases the risk of stroke and blood clots in large veins. Estrogens with or without progestins should not be used for prevention of heart disease or stroke. Estrogens with or without progestins should be used at the lowest effective dose and for the shortest time period possible. Keep your follow-up with your doctor regularly.

What Are The Possible Side Effects of Climara Patch?

Like all other medications, Climara Patch can also cause side effects. Most common side effects include breast pain, breast tenderness, bloating, dizziness, localized darkening of the skin, mood swings, redness or mild irritation under or around the patch, changes in the genital bleeding pattern (including breakthrough bleeding and spotting), headache, weight gain. Some of the uncommon side effects include muscle cramps and breast enlargement. Other side effects include abdominal pain, nausea or vomiting, changes in body weight, heavy periods, migraine headaches, persistent skin irritation, retention of fluid, unexpected vaginal bleeding, breast lumps, changes in speech and vision, crushing chest pain or chest heaviness, easy bruising, excessive nose bleeds, high blood pressure, pain or swelling in legs, persistent sad mood, rapid pulse, shortness of breath, coughing blood, Skin redness, warmth, swelling, tenderness, pain or hardening of tissue around a vein, sudden partial or complete loss of vision, vaginal yeast infection, liver problems such as jaundice, hair loss, enlargement of benign tumors of the uterus ("fibroids"). Less common but serious side effects include breast cancer, cancer of the uterus, stroke, blood clots, dementia, heart attack, gallbladder disease and ovarian cancer. These are not all the side effects of using a Climara Patch. If you experience any unexpected effect, immediately consult your doctor.

When Should You Not Use A Climara Patch?

Do not use Climara Patch if you:
  • Are pregnant or breastfeeding
  • Have an active liver disease or have had a liver tumor in the past
  • Have a history of certain types of cancers such as cancer of the uterus
  • Have or had breast cancer
  • Have been diagnosed with endometrial hyperplasia (overgrowth of the lining of the uterus)
  • Have experienced undiagnosed or abnormal vaginal bleeding
  • Have a history of heart attack, heart disease or stroke
  • Have a history of blood clots or active thrombophlebitis (inflammation of veins)
  • Are at high risk of developing blood clots if you were born with certain blood clotting disorders
  • Have had partial or complete loss of vision due to a blood vessel disease of the eye
  • Have had an allergic or unusual reaction to estrogen or any other component of Climara Patch

What Should You Tell Your Doctor Before Using Climara Patch?

Before you start using Climara Patch, be sure to tell your doctor if you:
  • Have a history of allergy or intolerance to any medicines or other substances
  • Have a history of breast disease (such as breast lumps), breast biopsies or family history of breast cancer
  • Have experienced any unusual or undiagnosed vaginal bleeding
  • Have a history of uterine fibroids or endometriosis
  • Have a history of liver disease, jaundice (yellowing of eyes or skin), or itching due to estrogen use or during pregnancy
  • Have or have had chloasma (yellow-brown patches on the skin)
  • Have inherited deafness
  • Have systemic lupus erythematosus (SLE; a chronic inflammatory disease)
  • Have or have had chorea minor (illness with unusual movements)
  • Have condition called hereditary angioedema or if you had episodes of swelling of hands, face, feet, lips, eyes, tongue or throat, airway blockage or digestive tract
  • Have a history of migraine headaches
  • Have a history of high blood pressure
  • Have personal or family history of blood clots or a personal history of heart disease or stroke
  • Are going to have surgery or need long bed rest
  • Have or have had kidney disease, asthma or epilepsy
  • Have a history of bone disease (metabolic conditions or cancers that can affect blood levels of calcium and phosphorus)
  • Have been diagnosed with diabetes
  • Have been diagnosed with porphyria (a disease of blood pigment)
  • Have been diagnosed with high prolactin levels or prolactinoma
  • Have history of high cholesterol or high levels of triglycerides
  • Are pregnant or planning to become pregnant
  • Are breastfeeding
  • Have had a hysterectomy (surgical removal of uterus)
  • Smoke
  • Have a history of depression

What Medicines Can Interact With Climara Patch?

It is important to tell your healthcare professional about all other medicines that you have taken recently including any kind of supplements and non-prescription drugs.

Medicines which interact with Climara Patch include:
  • Anticoagulants such as warfarin
  • Antidiabetic agents such as metformin
  • Medicines used for the treatment of heart diseases or high blood pressure such as diltiazem, verapamil
  • Medicines used for the treatment of HIV infections and Hepatitis C Virus Infections such as nelfinavir, ritonavir
  • Barbiturates, carbamazepine, meprobamate, phenylbutazone, primidone, phenytoin, oxcarbazepine, topiramate, felbamate or rifampicin
  • Antibiotics such as erythromycin, clarithromycin, penicillin, tetracycline
  • Antifungal medications such as griseofulvin, fluconazole, itraconazole, ketoconazole, voriconazole
  • Antivirals such as ritonavir
  • Alcohol, grapefruit juice, and St. John's Wort can also interact with Climara Patch

Where Can I Buy Climara Patch Online?

If prescribed by your healthcare professional, Climara Patch can be bought directly from Canadian Online Pharmacy. You will not have to wait to start your therapy due to the swift shipping service provided by us.

How Is Climara Patch Delivered?

The standard delivery fee is $10.00. The orders are usually shipped in 2-3 working days after the processing of the order. The medication package is delivered by regular mail within 10-14 business days after it has been shipped.

For further information and aid, you can contact our Customer Service at 1877-240-4438 or email us at


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