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Atripla (Efavirenz/Emtricitabine/Tenofovir)

TypeDrug NameDosage 
Atripla600 mg/200 mg/300 mg

Generic Equivalent of Atripla

No generic equivalents of Atripla found.

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Is A Prescription Required To Purchase Atripla?

A Prescription is required to acquire Atripla from licensed online Canadian pharmacies.

What Is The Drug Atripla Used for?

The drug Atripla contains three medicines: Sustiva (efavirenz), Emtriva (emtricitabine) and Viread (tenofovir disoproxil fumarate) combined in one pill. Emtriva and Viread are HIV (human immunodeficiency virus) nucleoside/nucleotide analog reverse transcriptase inhibitors and Sustiva is and HIV non-nucleoside analog reverse transcriptase inhibitor. Atripla is used alone or in combination with other medications to treat patients with HIV infection. This medication is for use in adults above 18 years of age. Atripla has not been studied in children under 18 years or adults above 65 years of age.

How Does Atripla Work In The Body?

The drug Atripla helps to block the HIV reverse transcriptase chemical in the body that is needed for the HIV to multiply. It also lowers the amount of HIV load in the blood (also known as viral load). Lowering the amount of HIV in the blood also helps to decrease the chances of infections that can occur when your immune system is weak (known as opportunistic infections). Atripla may also help to increase the number of T cells in the body which help fight the infection. This medication does not cure HIV or AIDS, neither does it reduce the risk of passing HIV to others through sexual contact or blood contamination.

How Is Atripla Supplied and Stored?

Atripla is manufactured by Bristol-Myers Squibb and Gilead Sciences, LLC. The medication is available in the form of tablets. Each tablet contains 600 mg of efavirenz, 200 mg of emtricitabine and 300 mg of tenofovir disoproxil fumarate as the active ingredients. These are available in the packaging of 30 tablets.

The medication should be stored at a temperature between 15°C and 30°C, tightly closed in its original container. It should be kept out of sight and reach of children.

What Is the Cost of Atripla?

Our verified online pharmacy is pleased to offer you Atripla 600 mg/200 mg/300 mg at an unbeatable price of $1799 for a supply of 30 tablets, which is $59.97 per tablet. It is best to compare the prices of drugs online at edrugsearch or Pharmacychecker.Com.

Is Truvada The Same As Atripla?

While Atripla contains three active ingredients Sustiva, Emtriva, and Viread, Truvada contains two active ingredients Emtriva and Viread.

How Should You Take Atripla?

It is important to stay under a doctor’s care while taking Atripla. Take the medication exactly as prescribed by your doctor. The usual dose of Atripla is one tablet daily. It should be taken empty stomach. Taking Atripla at bedtime can make some of its side effects less bothersome. Do not stop the treatment without talking to your doctor. When your Atripla starts to run low, get more from your doctor or pharmacy. This is important because the viral load in your blood may increase if the medication is stopped even for a short period of time.

What Should I Avoid While Taking Atripla?

Atripla can lead to dizziness, trouble concentrating or drowsiness. Hence patients who experience such symptoms while taking this medication should avoid driving or operating heavy machinery.

Can You Drink Alcohol While Taking Atripla?

The effect of combining alcohol with Atripla has not been studied. Because they may interact with each other, speak with your doctor before you take alcohol with Atripla.

How is Atripla Metabolized in Body?

All the active components of Atripla, (efavirenz, emtricitabine, and tenofovir disoproxil fumarate) are metabolized in the liver. Efavirenz has a half-life of approximately 52-76 hours, emtricitabine has a half-life of 10 hours and tenofovir DF has a half-life of 17 hours.

How Safe Is Atripla?

The two components of Atripla, emtricitabine and tenofovir DF can lead to a condition called as lactic acidosis with an enlarged liver. This is a rare, but fatal side effect. Symptoms of lactic acidosis include weakness, tiredness, discomfort, unusual or unexpected stomach discomfort, feeling cold, dizziness or lightheadedness, suddenly developing an irregular heartbeat. This condition occurs more often in women, especially if they are overweight. You should consult your doctor immediately if such symptoms occur while you are receiving Atripla. Women who take Atripla should not become pregnant during the treatment and for 12 weeks after stopping the medication. Serious side effects have been reported in women treated with efavirenz (an active component of Atripla) during pregnancy. Always use a reliable method of contraception such as a pill or implants while taking this medication. If you become pregnant while taking Atripla, your doctor might register you in the Antiretroviral Pregnancy Registry. This Registry monitors fetal outcomes in pregnant women using antiretroviral medicines.

What Are The Possible Side Effects of Atripla?

Like all other medications, Atripla can also cause side effects. Common side effects include of Sustiva, Emtriva and Viread include dizziness, trouble sleeping, drowsiness, trouble concentrating, unusual dreams, headache, diarrhea, nausea, vomiting, rash, intestinal gas, tiredness, itching, allergic reaction including swelling of the face, lips, tongue or throat, abdominal pain, inflammation of the pancreas, shortness of breath, skin discoloration. A small number of patients taking the efavirenz component of Atripla have reported symptoms of depression, strange thoughts, angry behavior, and suicidal thoughts. Contact your doctor if you think you are having these symptoms so your doctor can decide whether you should continue to take Atripla or not. Antiretroviral therapy can cause changes in body fat such as the increased amount in the upper back and neck (buffalo hump), breast and around the trunk, loss of fat from legs, arms and face. Some patients have also experienced liver failure resulting in transplantation or death. HIV medicines can also cause changes in your immune system (Immune Reconstitution Inflammatory Syndrome). Your immune system may get stronger and begin to fight infections that had been hidden in the body for a long time. You can also develop an autoimmune disease in which your immune system reacts against your own body such as Grave’s disease (a disease that affects the thyroid gland). Some other side effects include catatonia (cannot move or talk for some time), severe liver problems with liver enlargement with symptoms such as jaundice (skin or the white part of eyes turns yellow), urine turns dark, bowel movements (stools) turn light in color, loss of appetite for several days or longer, nausea, lower stomach pain, kidney problems with increased or decreased urination, increased thirst, swelling of legs and feet, tiredness. Flare-ups of hepatitis B virus infection may occur following drug discontinuation. These are not all the possible side effects of Atripla. In case of any unexpected effect, contact your healthcare professional immediately.

When Should You Not Take Atripla?

Do not take Atripla if you:
  • Are allergic to efavirenz, emtricitabine, and tenofovir DF or any other ingredients in Atripla
  • Have or are at a risk for any bone disease
  • Are taking Propulsid (cisapride), Versed (midazolam), Halcion (triazolam), ergot medications (for example Wigraine and Cafergot), Hismanal (astemizole), Seldane (terfenadine), Vascor (bepridil), or Orap (pimozide). Taking these medications with Atripla can result in serious or life-threatening side effects.
  • Are taking Vfend (voriconazole) since it may lose its effect or may increase the chance of having side effects from Atripla
  • Are taking St. John’s Wort or any products containing this herbal ingredient. Taking St. John’s Wort may decrease Atripla levels and may lead to increased viral load and possible resistance to efavirenz.

What Should You Tell Your Doctor Before taking Atripla?

Before you start taking Atripla, be sure to tell your doctor if you:
  • Are breastfeeding or planning to breastfeed. Do not breastfeed if you have HIV or are taking Atripla. HIV can be passed to your baby through your breast milk. All components of Atripla (efavirenz, emtricitabine, and tenofovir DF) can also pass through breast milk and cause harm to your baby. Talk to your doctor about the best way to feed your baby.
  • Have medical conditions such as liver or kidney problems
  • Suffer from pancreatitis (inflammation of the pancreas)
  • Suffer from seizures or a mental illness
  • Have or are at a risk for bone disease or bone-related problems
  • Have irregular heartbeat
  • Suffer from prolonged QT interval
  • Have a heart condition known as Torsades de pointes
  • Are taking other medications including prescription and over the counter medications

What Medicines Can Interact With Atripla?

It is important to tell your healthcare professional about all other medicines that you have taken recently including any kind of supplements and non-prescription drugs.

Medicines which interact with Atripla include:
  • Propulsid (cisapride), Versed (midazolam), Halcion (triazolam), ergot medications (for example Wigraine and Cafergot), Hismanal (astemizole), Seldane (terfenadine), Vascor (bepridil), or Orap (pimozide). Taking these medications with Atripla can result in serious or life-threatening side effects.
  • Vfend (voriconazole) since it may lose its effect or may increase the chance of having side effects from Atripla
  • St. John’s Wort or any products containing this herbal ingredient. Taking St. John’s Wort may decrease Atripla levels and may lead to increased viral load and possible resistance to efavirenz.
  • 3TC, Combivir, Complera, Descovy, Emtriva, Genvoya, Heptovir, Hepsera, Kivexa, Triumeq, Trizivir, Truvada, Stribild, Viread, Sustiva
  • Cidofovir, ganciclovir, vancomycin or aminoglycosides
  • Reyataz (atazanavir sulfate), Fortovase or Invirase (saquinavir)
  • Biaxin (clarithromycin)
  • Celsentri (maraviroc), Crixivan (indinavir), methadone, Mycobutin (rifabutin), Zoloft (sertraline), Wellbutrin SR, WellbutrinXL, or Zyban (bupropion)
  • Videx or Videx EC (didanosine)
  • Kaletra (lopinavir/ritonavir) or Harvoni (ledipasvir/sofosbuvir)
  • Epclusa (sofosbuvir/velpatasvir)
  • Medicines for seizures, for example, Dilantin (phenytoin), Tegretol (carbamazepine), or phenobarbital
  • Sporanox (itraconazole) and Posanol (posaconazole)
  • The cholesterol-lowering medicines Lipitor (atorvastatin), Pravachol (pravastatin sodium), and Zocor (simvastatin).
  • Rifadin (rifampin) or the rifampin-containing medicines Rofact and Rifater
  • Calcium channel blockers such as Cardizem or Tiazac (diltiazem), Covera HS, Isoptin SR or Tarka (verapamil), and others.
  • Immunosuppressants such as Neoral (cyclosporine), Advagraf or Prograf (tacrolimus), Rapamune or Torisel (sirolimus)
  • Hepatitis C antiviral agents such as Victrelis (boceprevir), Galexos (simeprevir) and Incivek (telaprevir)
  • Antimalarials such as Coartem and Riamet (artemether/lumefantrine), Malarone (atovaquone/proguanil)

Where Can I Buy Atripla Online?

If prescribed by your healthcare professional, Atripla can be bought directly from Canadian Online Pharmacy. You will not have to wait to start your therapy due to the swift shipping service provided by us.

How Is Atripla Delivered?

The standard delivery fee is $10.00. The orders are usually shipped in 2-3 working days after the processing of the order. The medication package is delivered by regular mail within 10-14 business days after it has been shipped.

For further information and aid, you can contact our Customer Service at 1877-240-4438 or email us at customerservice@canadawidepharmacy.com.

References:

1. https://www.bms.com/assets/bms/ca/documents/productmonograph/ATRIPLA_EN_PM.pdf
2. https://www.gilead.com/-/media/files/pdfs/medicines/hiv/atripla/atripla_pi.pdf?la=en
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