Is A Prescription Required To Purchase Estring?
A Prescription is required to acquire Estring from licensed online Canadian pharmacies.
What Does The Estring Do?
Estring is a vaginal ring used for relieving the postmenopausal vaginal (dryness, burning, pruritus and painful sexual intercourse) and urinary symptoms (urinary urgency and dysuria) associated with estrogen deficiency.
How Does Estring Work?
Estring is an estradiol vaginal ring that contains a reservoir of 2 mg estradiol (an estrogen). This vaginal ring slowly releases estrogen into the vagina in a stable and consistent manner. Estrogens are hormones produced by a woman's ovaries. When her menstrual periods stop (menopause) around the age of 45-50, the ovaries stop producing estrogens. Sometimes ovaries are removed by an operation and it is known as surgical menopause. The drop in estrogen levels causes uncomfortable symptoms in women such as thinning and dryness of the tissue of urinary tract and vagina, vaginal dryness, genital itching, burning and pain with intercourse, a sensation of urinary urgency and pain while urinating.
How Is Estring Supplied and Stored?
Estring is manufactured by Pfizer Canada Inc. and is available as estradiol vaginal ring in single units. Each unit contains 2 mg estradiol.
The medication should be stored at a controlled room temperature between 15°C and 30°C. It should be kept out of sight and reach of children and pets.
What Is the Cost of Estring?
Our verified online pharmacy is pleased to offer you the Estring Vaginal Ring 2 mg at an unbeatable price of $349 for a supply of 3 tabs, which is $116.33 per tab. It is best to compare the prices of drugs online at edrugsearch or Pharmacychecker.Com.
How Long Does It Take For Estring To Work?
The Estring vaginal ring usually about 2 to 3 weeks to restore the health of the vaginal and urinary tract tissue and provide complete relief from vaginal and urinary symptoms. If your symptoms persist more than a few weeks after the start of Estring therapy, consult your doctor.
Can Estring Be Used During A Vaginal Infection?
During treatment for vaginal infection, it is recommended to discontinue Estring therapy. Use of Estring can be resumed after termination of other vaginal medications and after consulting with your doctor.
How Long Does Estring Stay In?
An Estring vaginal ring is to be worn continuously for 90 days. Most women and their partners do not experience any discomfort with Estring during sexual intercourse, so it is not necessary to remove the ring. Estring may sometimes slide down into the lower part of your vagina due to abdominal pressure or strain accompanied by constipation. If this happens, then slightly guide the ring back into its place with your finger. Some rare cases of ring falling out in some women due to straining or coughing have been reported. In such a case, simply wash the ring with lukewarm water and reinsert it.
How Should The Estring Be Removed After 90 Days?
After completion of 90 days, Estring no longer contains enough estradiol to maintain its full effect in relieving the vaginal or urinary symptoms. Estring should be removed after 90 days and replaced with a new Estring if your doctor decides to continue your therapy. In order to remove Estring wash and dry your hands thoroughly, take a comfortable position standing with one leg up, squatting or lying down. Then loop your finger through the ring and pull it out gently. Discard the ring in a waste receptacle, but do not flush it.
What Is The Maximum Duration Of Treatment With Estring?
The maximum duration of treatment recommended for treatment with Estring is 2 years. However, this medication should be used under the careful supervision of a doctor, with regular follow-up at least once a year to find out the side effects associated with its use. Tests may include blood pressure check-up, breast exam, a Pap smear and pelvic exam. It is recommended to undergo a mammogram before starting the treatment and at regular intervals.
Can I Get An X-ray While Using Estring?
If you have to undergo any X-ray procedures of the lower abdominal tract, remove your Estring since the barium sulfate-containing core is visible on the X-ray and can disturb the procedure or evaluation of the X-ray exam.
How Safe Is The Treatment With Estring?
Before considering starting with the Estring vaginal ring, you should be aware of the important health risks involved with its use. Estring use causes an increased risk of development of invasive breast cancer, ovarian cancer, dementia, heart attack, stroke and blood clots in both lungs and large veins if used along with progestin therapy. Estrogen alone therapy also causes an increased risk of stroke and blood clots in the large veins. Estrogen treatment with or without progestin should be used at the lowest effective dose and for the shortest period of time possible. You should follow-up with your doctor regularly during the entire duration of therapy with Estring. A few cases of Toxic Shock Syndrome (TSS) have been reported in women who use vaginal rings. Some warning symptoms of TSS include fever, nausea, vomiting, diarrhea, muscle pain, dizziness, faintness, or a sunburn-rash on face and body.
What Are The Possible Side Effects of Estring?
Like all other medications, Estring can also cause side effects. Most common side effect with the use of Estring increased vaginal secretions. These secretions are similar to those that occur prior to menopause and indicate that Estring is working. Vaginal secretions which are associated with bad smell, vaginal itching, or other signs of vaginal infection are not normal and indicate a risk or concern. Some other side effects include vaginal discomfort, pain in the abdomen, genital itching, vaginal bleeding or spotting, headache, breast tenderness, leg swelling, toxic shock syndrome, adherence to the vagina making it difficult to remove the ring, blockage of the bowel. Some cases of allergic reactions such as itching, hives, swelling, vaginal discomfort/irritation, redness, along with hospitalization have also been reported with the use of vaginal rings. Some other side effects reported with use of estrogens are breast tenderness or enlargement, retention of excess fluid leading to worsening of asthma, epilepsy, migraine, heart or kidney disease, spotty darkening of the skin, especially on the face. Some serious side effects of Estring include abnormal bleeding from vagina, pain in calves or chest, sudden shortness of breath, coughing blood, severe headache, vomiting, seizures, dizziness, fainting, changes in vision or speech, visual disturbances, breast lumps, weakness or numbness of an arm or leg, pain, swelling or tenderness in abdomen, yellowing of eyes or skin, toxic shock syndrome (TSS), and persistent sad mood. These are not all the possible side effects of the Estring vaginal ring. In case of any unexpected effect, contact your doctor immediately.
When Should You Not Use Estring?
Do not use Estring if you:
- Have a personal history of breast cancer
- Have a personal or family history of uterus cancer (endometrial cancer)
- Have been diagnosed with an overgrowth of the lining of the uterus (endometrial hyperplasia)
- Have experienced undiagnosed abnormal vaginal bleeding
- Have blood clot disorders such as blood clots in the leg or lungs
- Have liver disease
- Have vision loss due to a blood vessel disease
- Have or had a stroke, heart attack or coronary artery disease (disease of the blood vessels of the heart)
- Have or had porphyria((a rare disorder where you have a deficiency of enzymes involved in the production of heme)
- Have some types of congenital coagulation abnormalities (such as protein C, protein S or antithrombin deficiency)
- Are pregnant or planning to become pregnant
- Are breastfeeding
- Have or had an unusual allergic reaction to any of the ingredients in Estring
What Should You Tell Your Doctor Before Using Estring?
Before you start using Estring, be sure to tell your doctor if you:
- Have a history of allergy or intolerance to medications or other substances
- have a personal history of breast disease (including breast lumps) and/or breast biopsies
- Have a family history of breast cancer
- Have experienced unusual vaginal bleeding
- Have a history of uterine fibroids or endometriosis
- Have a history of liver disease, jaundice or itching related to use of estrogen or during pregnancy
- Have a history of a migraine headache
- Have a history of high blood pressure
- Have a personal or family history of blood clots, or heart disease or stroke
- Have a history of kidney disease
- Have a history of asthma or seizures
- Have been diagnosed with diabetes
- Are pregnant or may be pregnant
- Are breastfeeding
- Have a vaginal infection
- Smoke
- Have been diagnosed with porphyria (a rare disorder where you have a deficiency of enzymes involved in the production of heme)
- Have a history of high cholesterol or triglyceride levels in the blood
- Have a history of bone diseases such as metabolic conditions, cancers that can affect the levels of potassium and calcium
- Have had a hysterectomy (surgical removal of the uterus)
- Have a family history of angioedema
What Medicines Can Interact With Estring?
It is important to tell your healthcare professional about all other medicines that you have taken recently including any kind of supplements and non-prescription drugs.
Medicines which interact with Estring include:
- Anticoagulants such as warfarin, heparin
- Antidiabetic agents such as metformin
- Medicines used to treat high blood pressure
- Barbiturates like phenobarbital used to treat seizures
- Antibiotics such as erythromycin, clarithromycin, ketoconazole, itraconazole, ritonavir
Where Can I Buy Estring Online?
If prescribed by your healthcare professional, Estring can be bought directly from Canadian Online Pharmacy. You will not have to wait to start your therapy due to the swift shipping service provided by us.
How Is Estring Delivered?
The standard delivery fee is $10.00. The orders are usually shipped in 2-3 working days after the processing of the order. The medication package is delivered by regular mail within 10-14 business days after it has been shipped.
For further information and aid, you can contact our Customer Service at 1877-240-4438 or email us at
customerservice@canadawidepharmacy.com.
References:
1. https://www.pfizer.ca/sites/g/files/g10017036/f/201410/Estring_PM_E_10.pdf
2. https://www.pfizer.ca/sites/g/files/g10023411/f/201506/Estring_PI_E.pdf
3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020472s007lbl.pdf