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Canada Wide Pharmacy > Drug Category > Women's Health > Estrace or Equivalent

Estrace (Estradiol)

No brand of Estrace found.

Generic Equivalent of Estrace

TypeDrug NameDosage 
Estradiol (Tablet)0.5 mg
Estradiol (Tablet)1 mg
Estradiol (Tablet)2 mg

Is A Prescription Required To Purchase Estrace?

A Prescription is required to acquire Estrace from licensed online pharmacies CanadaWide.

Why Is Estrace Prescribed?

Estrace is indicated for:
  • Treatment of menopause symptoms (moderate to severe hot flashes). Estrogens are hormones produced by a woman's ovaries. When her menstrual periods stop (menopause), around the age of 45-50, the ovaries stop producing estrogens. Sometimes ovaries are removed by an operation and it is known as surgical menopause. The drop in estrogen levels causes uncomfortable symptoms in women such as the feeling of warmth in face, neck, and chest or a sudden intense episode of heat and sweating (known as hot flashes). These hot flashes can further lead to frequent awakening at night, irritability, sleep disturbance and depression.
  • Treatment of moderate to severe dryness, itching, burning and itching around the vagina, which occurs due to estrogen deficiency.
  • Prevention of the development of osteoporosis (thinning of bones that makes them weaker and easier to break) when combined with other important therapeutics such as diet, calcium and vitamin D intake, smoking cessation, and regular physical weight-bearing exercises.
Estrace should be used only under the supervision of a doctor, with regular follow-up at least once a year to identify possible side effects associated with its use. Your first follow-up visit should be within 3 to 6 months of the start of treatment. Your visit may include a blood pressure check, a breast exam, a Pap smear and pelvic exam. You should have a mammogram before starting treatment and at regular intervals as recommended by your doctor. if you still have a uterus, talk to your doctor about the addition of a progestin (another female hormone) to your therapy in order to prevent cancer of the uterus.

How Does Estrace Work in the Body?

Estrace contains 17β-estradiol and works by replacing the diminished estrogen production by the body. Estrogens are female hormones that are produced by the body and are required for the normal sexual development and regulation of menstrual periods during the childbearing years. Low estrogen levels during menopause can lead to osteoporosis (thinning of bones) and postmenopausal symptoms. Estrace helps to relieve postmenopausal symptoms and prevent osteoporosis.

Is There A Generic Form Of Estrace?

The generic form of Estrace is estradiol and is manufactured by Lupin.

How Is Estrace Supplied and Stored?

Estrace is manufactured by Acerus Pharmaceuticals and is available in dosage forms of 0.5 mg, 1 mg and 2 mg in the bottles of 100 tablets.

The generic form of Estrace (estradiol) is available in the dosage forms of 0.5 mg, 1 mg and 2 mg in the packaging of 100 tablets.

Estrace should be stored at room temperature between 15°C and 30°C, in a tightly closed container, protected from light. It should be kept out of sight and reach of children.

What Is the Cost of Estrace?

Our verified online pharmacy is pleased to offer you the Estrace 0.5 mg at an unbeatable price of $45 for a supply of 100 tablets, which is $0.45 per unit. The generic form of Estrace (estradiol) is available at a price of $39, for a supply of 100 tablets, which is 0.39 per unit. It is best to compare the prices of drugs online at edrugsearch or Pharmacychecker.Com.

Is Estrace A Bioidentical Hormone?

Bioidentical hormones are the manufactured copies of the same hormone that your body uses. Some of the FDA approved therapies for menopause such as Estrace contain the same bioidentical form of estrogen as the hormone formulations compounded in a pharmacy.

Are Estradiol And Estrace The Same?

Estrace contains the active ingredient as estradiol. Estradiol is the generic form of Estrace.

Does Estrogen Make You Gain Weight?

HRT (hormone replacement therapy) such as Estrace can lead to changes in body weight such as weight gain.

Is Estrogen Cancer Causing?

Estrogen is cancer causing when used for prolonged periods of time. Estrogen can increase the risk of breast cancer, uterine cancer, and ovarian cancer.

How Long Does It Take To Feel The Effects Of Hormone Replacement Therapy?

It might take a few weeks before you feel the benefits of hormone replacement therapy (HRT) such as Estrace. It can take up to three months to feel the complete effects of the therapy.

How Should You Take Estrace?

Take the medication exactly as prescribed by your doctor. Your doctor will prescribe the lowest dose of estrogen to treat menopausal symptoms or prevent osteoporosis. Estrogen is usually administered for the first 21 days to 25 days of each month. Take one tablet of Estrace at the same time each day. If your uterus has been removed, you will take this medication every day of the month. If you still have a uterus, you will take Estrace on certain days of the month as directed by the doctor. You will also take a progestin on certain days of the month in order to prevent abnormal growth of the lining of the uterus. Your doctor may adjust your dose according to your needs.

Can I Drink Alcohol While Taking Estrace?

It is good to avoid alcohol while taking Estrace as acute alcohol intake while taking Estrace can lead to increased levels of circulating estradiol.

Can I Drink Grapefruit Juice While Taking Estrace?

Grapefruit Juice can increase the concentrations of estrogen in the body, resulting in side effects. Hence, drinking grapefruit juiced should be avoided while taking Estrace.

How Safe Is Estrace?

Use of estrogens with progestins can lead to increased risk of developing breast cancer, heart attack, stroke and blood clots in both lungs and large veins. Use of estrogen alone therapy increases the risk of stroke and blood clots in large veins. Estrogens with or without progestins should not be used for prevention of heart disease or stroke. Estrogens with or without progestins should be used at the lowest effective dose and for the shortest time period possible. Keep your follow-up with your doctor regularly.

What Are The Possible Side Effects of Estrace?

Like all other medications, Estrace can also cause side effects. Most common side effects include breast pain and swelling, breast tenderness, irregular vaginal bleeding or spotting, vaginal itching/discharge or pain, depression, nervousness, irritability, allergic reaction and rash, hair loss or abnormal hair growth, increased blood sugar levels, change in blood pressure, change in weight, acne, change in cholesterol or triglyceride levels, stomach cramps, bloating, headache, dizziness, abdominal pain, nausea and vomiting. Many women, who take estrogens with a progestin will at the start have monthly vaginal bleeding, similar to menstrual periods again. This effect will continue for as long as the medicine is taken. Some uncommon side effects of Estrace include lumps or discharge from the breast, crushing chest pain or chest heaviness, pain in the groin, pain or swelling in the leg or feet, persistent sad mood, sharp pain in the chest, coughing blood or sudden shortness of breath, sudden partial or complete loss of vision, sudden loss of coordination, fainting, disturbance of speech or vision, weakness or numbness in an arm or leg, yellowing of skin, unexpected vaginal bleeding. These are not all the possible side effects of Estrace. In case of any unexpected effect, consult your healthcare professional immediately.

When Should You Not Take Estrace?

Do not take Estrace if you:
  • Are pregnant or breastfeeding
  • Have a liver disease
  • Have or had a history of certain types of cancers such as cancer of the uterus
  • Have or had a history of breast cancer
  • Have been with endometrial hyperplasia (overgrowth of the lining of the uterus)
  • Have experienced undiagnosed or abnormal vaginal bleeding
  • Have a history of heart attack, heart disease, angina or stroke
  • Have migraines
  • Have a history of blood clot disorders including blood clots in the legs or lungs or active thrombophlebitis (blood clots and inflammation of veins)
  • Are at high risk of developing blood clots if you were born with certain blood clotting disorders
  • Have had partial or complete loss of vision due to a blood vessel disease of the eye
  • Have had an allergic or unusual reaction to estrogen or any other component of Estrace tablets

What Should You Tell Your Doctor Before Taking Estrace?

Before you start taking Estrace, be sure to tell your doctor if you:
  • Have a history of allergy or intolerance to any medicines or other substances
  • Have a history of breast disease (such as breast lumps), breast biopsies or family history of breast cancer
  • Have experienced any unusual or undiagnosed vaginal bleeding
  • Have a history of uterine fibroids or endometriosis
  • Have a history of liver disease, jaundice (yellowing of eyes or skin), or itching due to estrogen use or during pregnancy
  • Have a history of a migraine headache
  • Have a history of high blood pressure
  • Have personal or family history of blood clots or a personal history of heart disease or stroke
  • Are going to have surgery or need long bed rest
  • Have or have had kidney disease, asthma or epilepsy
  • Have a history of bone disease (metabolic conditions or cancers that can affect blood levels of calcium and phosphorus)
  • Have been diagnosed with diabetes
  • Have been diagnosed with porphyria (a disease of blood pigment)
  • Have a history of high cholesterol or high levels of triglycerides
  • Are pregnant or planning to become pregnant
  • Are breastfeeding
  • Have had a hysterectomy (surgical removal of the uterus)
  • Have a history of depression.

What Medicines Can Interact With Estrace?

It is important to tell your healthcare professional about all other medicines that you have taken recently including any kind of supplements and non-prescription drugs.

Medicines which interact with Estrace include:
  • Anticoagulants such as warfarin
  • Antidiabetic agents such as metformin
  • Medicines used for the treatment of heart diseases or high blood pressure such as diltiazem, verapamil
  • Medicines used to prevent inflammation such as medicines containing phenylbutazone
  • Medicines used to control epilepsy such as barbiturates, carbamazepine, primidone, phenytoin
  • Medicines used to control anxiety such as meprobamate
  • Medicines used to treat a bacterial infection such as rifampicin
  • Grapefruit juice, and St. John's Wort

Where Can I Buy Estrace Online?

If prescribed by your healthcare professional, Estrace can be bought directly from Canadian Online Pharmacy. You will not have to wait to start your therapy due to the swift shipping service provided by us.

How Is Estrace Delivered?

The standard delivery fee is $10.00. The orders are usually shipped in 2-3 working days after the processing of the order. The medication package is delivered by regular mail within 10-14 business days after it has been shipped.

For further information and aid, you can contact our Customer Service at 1877-240-4438 or email us at


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